We're thrilled to announce the publication of a groundbreaking systematic review and meta-analysis led by Dr. Greg Marchand and the dedicated research team at the Marchand Institute for Minimally Invasive Surgery! Titled "Laparoendoscopic Single-Site Surgery Versus Conventional Laparoscopic Surgery in Ovarian Cystectomy: A Meta-Analysis", this comprehensive study compares two advanced minimally invasive techniques for removing benign ovarian cysts — Laparoendoscopic Single-Site Surgery (LESS) (using a single small incision, often hidden at the umbilicus for superior cosmetic results) and Conventional Laparoscopic Surgery (CLS) (using multiple small incisions). Analyzing data from 9 studies involving 1,368 women, the meta-analysis reveals compelling insights: LESS is associated with longer operative times (by about 9.4 minutes on average), likely due to the technical demands of working through a single port. However, patients undergoing LESS benefit from a shorter hospital stay (reduced by approximately 0.26 days). Importantly, there are no significant differences in key safety outcomes: postoperative pain scores (at 6 and 24 hours), estimated blood loss, need for opioid analgesics, drop in hemoglobin levels, or overall complication rates. These findings strengthen the evidence that LESS is a safe, effective, and viable alternative to conventional laparoscopy for women with benign ovarian cysts — offering faster recovery and excellent cosmetic advantages while maintaining comparable safety and pain profiles. This work adds valuable high-level evidence to the field of minimally invasive gynecologic surgery and reflects the Marchand Institute's ongoing commitment to advancing women's health through rigorous, volunteer-driven research. Read the full open-access paper for free today: PubMed Central (PMC) (recommended - full text & PDF): https://pmc.ncbi.nlm.nih.gov/articles/PMC12734174/ Direct PDF download: https://pmc.ncbi.nlm.nih.gov/articles/PMC12734174/pdf/jcm-14-08739.pdf Published in Journal of Clinical Medicine (December 10, 2025) – DOI: 10.3390/jcm14248739 We invite clinicians, researchers, and patients interested in the latest advancements in minimally invasive surgery to explore this important contribution. A huge thank you to our incredible team of researchers, students, and collaborators who made this possible — all volunteer efforts dedicated to improving outcomes for women everywhere! Visit us at marchandinstitute.org to learn more about our ongoing research, educational programs, and mission to push the boundaries of minimally invasive techniques.

Newest Paper on Laparoscopic Single Site Ovarian Cystectomy Online Now!

We’re thrilled to announce the publication of a groundbreaking systematic review and meta-analysis led by Dr. Greg Marchand and the dedicated research team at the Marchand Institute for Minimally Invasive Surgery! Titled “Laparoendoscopic Single-Site Surgery Versus Conventional Laparoscopic Surgery in Ovarian Cystectomy: A Meta-Analysis”, this comprehensive study compares two advanced minimally invasive techniques for removing…

Laparoscopy, Laproscopy, Minimally Invasive Surgery, OBGYN

New Systematic Review Reveals Gynecologic Surgeons Achieve Superior Outcomes in Pediatric Adnexal Mass Surgery – Now Freely Available Online!

Dr. Marchand is thrilled to announce that his latest systematic review is now officially published and freely available online today! Titled “Comparison of the Surgical Treatment of Adnexal Masses in Pediatric and Adolescent Patients by Gynecologic Surgeons versus Pediatric Surgeons, a Systematic Review”, this work—led by Greg J. Marchand and colleagues from the Marchand Institute…

Laparoscopy, Minimally Invasive Surgery, OBGYN

Dr. Marchand back in EJOG with a New Article on The Latest Generation of MIGS Techniques

Dr. Marchand is thrilled to be back in EJOG this month with his newest publication on the latest generation of MIGS Techniques.  This paper looks into new techniques, including miniature and single port techniques. The paper is called : “Comparative efficacy and safety of newest generation minimally invasive techniques in hysterectomy: A meta-analysis of miniature…

Laparoscopy, Laproscopy, Minimally Invasive Surgery, OBGYN

Dr. Marchand’s Latest Work on VNOTES online Now!

Dr. Marchand’s Latest work on the subject of VNOTES, “The feasibility and surgical outcomes of robotic vaginal natural orifice transluminal endoscopic single port hysterectomy for benign gynecologic diseases: a systematic review and meta-analysis” is now available online.  The paper is open-access and freely accessable through the original publisher at AJOG Global Reports, as well as…

Laparoscopy, Laproscopy, Minimally Invasive Surgery, OBGYN, Uncategorized

Dr. Marchand’s New Analysis on Adnexectomy Online Today!

The latest publication from Dr. Greg Marchand, “Comparative analysis of laparoendoscopic single-site surgery and versus conventional laparoscopic surgery in adnexectomy: A systematic review and metaanalysis of surgical outcomes,” is online today! You can view the publication online at NIH’s Pubmed System (https://pubmed.ncbi.nlm.nih.gov/40062714/) or at the publishing journal’s website (https://tjoddergisi.org/articles/comparative-analysis-of-laparoendoscopic-single-site-surgery-and-versus-conventional-laparoscopic-surgery-in-adnexectomy-a-systematic-review-and-meta-analysis-of-surgical-outcome/doi/tjod.galenos.2025.09804).

Laparoscopy, Laproscopy, Minimally Invasive Surgery, OBGYN

New Analysis on Single Port Ectopic Pregnancy Now Available Online

Dr. Greg Marchand’s Institute’s latest paper, “Noninferiority of single-incision laparoscopy vs conventional laparoscopy in salpingectomy or salpingotomy for ectopic pregnancy: a meta-analysis” is now available free online. You can read the paper with at Elsevier’s Website for the publishing journal (American Journal of Obstetrics and Gynecology – Global Reports), or on the government’s National Institute…

Laparoscopy, Laproscopy, Minimally Invasive Surgery, OBGYN

Dr. Marchand’s Study on Laparoscopic vs. Vaginal Hysterectomy in Green Journal Today

Dr. Marchand’s major study entitled “Vaginal Hysterectomy Compared With Laparoscopic Hysterectomy in Benign Gynecologic Conditions: A Systematic Review and Meta-analysis” appears online today in the Green Journal (Obstetrics & Gynecology). This is the largest study to date comparing the advantages and safety of vaginal hysterectomy versus laparoscopic, and has some very interesting findings! Click here…

Laparoscopy, Laproscopy, Minimally Invasive Surgery, OBGYN