New Systematic Review and Meta-Analysis: Comparative Risk of Neonatal Ischemic Encephalopathy in Operative Vaginal Delivery vs. Cesarean at Complete Dilation – Now Online in AJP!

We are excited to announce our latest publication is now available online ahead of print in the American Journal of Perinatology! “Comparative Risk of Neonatal Ischemic Encephalopathy in Operative Vaginal Delivery Versus Cesarean Section at Complete Dilation: A Systematic Review and Meta-Analysis.” is now available online at this link: https://www.thieme-connect.de/products/ejournals/abstract/10.1055/a-2796-1349 This systematic review and meta-analysis…

We're thrilled to announce the publication of a groundbreaking systematic review and meta-analysis led by Dr. Greg Marchand and the dedicated research team at the Marchand Institute for Minimally Invasive Surgery! Titled "Laparoendoscopic Single-Site Surgery Versus Conventional Laparoscopic Surgery in Ovarian Cystectomy: A Meta-Analysis", this comprehensive study compares two advanced minimally invasive techniques for removing benign ovarian cysts — Laparoendoscopic Single-Site Surgery (LESS) (using a single small incision, often hidden at the umbilicus for superior cosmetic results) and Conventional Laparoscopic Surgery (CLS) (using multiple small incisions). Analyzing data from 9 studies involving 1,368 women, the meta-analysis reveals compelling insights: LESS is associated with longer operative times (by about 9.4 minutes on average), likely due to the technical demands of working through a single port. However, patients undergoing LESS benefit from a shorter hospital stay (reduced by approximately 0.26 days). Importantly, there are no significant differences in key safety outcomes: postoperative pain scores (at 6 and 24 hours), estimated blood loss, need for opioid analgesics, drop in hemoglobin levels, or overall complication rates. These findings strengthen the evidence that LESS is a safe, effective, and viable alternative to conventional laparoscopy for women with benign ovarian cysts — offering faster recovery and excellent cosmetic advantages while maintaining comparable safety and pain profiles. This work adds valuable high-level evidence to the field of minimally invasive gynecologic surgery and reflects the Marchand Institute's ongoing commitment to advancing women's health through rigorous, volunteer-driven research. Read the full open-access paper for free today: PubMed Central (PMC) (recommended - full text & PDF): https://pmc.ncbi.nlm.nih.gov/articles/PMC12734174/ Direct PDF download: https://pmc.ncbi.nlm.nih.gov/articles/PMC12734174/pdf/jcm-14-08739.pdf Published in Journal of Clinical Medicine (December 10, 2025) – DOI: 10.3390/jcm14248739 We invite clinicians, researchers, and patients interested in the latest advancements in minimally invasive surgery to explore this important contribution. A huge thank you to our incredible team of researchers, students, and collaborators who made this possible — all volunteer efforts dedicated to improving outcomes for women everywhere! Visit us at marchandinstitute.org to learn more about our ongoing research, educational programs, and mission to push the boundaries of minimally invasive techniques.

Newest Paper on Laparoscopic Single Site Ovarian Cystectomy Online Now!

We’re thrilled to announce the publication of a groundbreaking systematic review and meta-analysis led by Dr. Greg Marchand and the dedicated research team at the Marchand Institute for Minimally Invasive Surgery! Titled “Laparoendoscopic Single-Site Surgery Versus Conventional Laparoscopic Surgery in Ovarian Cystectomy: A Meta-Analysis”, this comprehensive study compares two advanced minimally invasive techniques for removing…

New Systematic Review Reveals Gynecologic Surgeons Achieve Superior Outcomes in Pediatric Adnexal Mass Surgery – Now Freely Available Online!

Dr. Marchand is thrilled to announce that his latest systematic review is now officially published and freely available online today! Titled “Comparison of the Surgical Treatment of Adnexal Masses in Pediatric and Adolescent Patients by Gynecologic Surgeons versus Pediatric Surgeons, a Systematic Review”, this work—led by Greg J. Marchand and colleagues from the Marchand Institute…

Dr. Marchand’s Analysis of Self Collected Pap Smears online today in AJOG!

Dr. Marchand’s Analysis of Self Collected Pap Smears is online today in AJOG’s “Global Reports.” The paper, “Patient vs. clinician-collected cervical cytology for screening for CIN: a systematic review and meta-analysis.” You can view the paper online open access through the publisher (Elsevier): 10.1016/j.xagr.2025.100575, or through the US Government’s NIH website: https://pmc.ncbi.nlm.nih.gov/articles/PMC12615280/.

Dr. Marchand back in EJOG with a New Article on The Latest Generation of MIGS Techniques

Dr. Marchand is thrilled to be back in EJOG this month with his newest publication on the latest generation of MIGS Techniques.  This paper looks into new techniques, including miniature and single port techniques. The paper is called : “Comparative efficacy and safety of newest generation minimally invasive techniques in hysterectomy: A meta-analysis of miniature…

Dr. Marchand’s Newest Paper on Marijuana Use in Pregnancy is Now Online!

Dr. Marchand’s Newest Paper on Marijuana Use in Pregnancy is Now Online! The latest meta analysis comparing outcomes for pregnancies exposed to marijuana is now online and free to read!  You can see the full paper here at the publisher’s website: https://mhnpjournal.biomedcentral.com/articles/10.1186/s40748-025-00216-9  Or on the US Government’s Pubmed Website Here: https://pubmed.ncbi.nlm.nih.gov/40745566/

 

Dr. Marchand’s Latest Work on VNOTES online Now!

Dr. Marchand’s Latest work on the subject of VNOTES, “The feasibility and surgical outcomes of robotic vaginal natural orifice transluminal endoscopic single port hysterectomy for benign gynecologic diseases: a systematic review and meta-analysis” is now available online.  The paper is open-access and freely accessable through the original publisher at AJOG Global Reports, as well as…

New Analysis on Single Port Ectopic Pregnancy Now Available Online

Dr. Greg Marchand’s Institute’s latest paper, “Noninferiority of single-incision laparoscopy vs conventional laparoscopy in salpingectomy or salpingotomy for ectopic pregnancy: a meta-analysis” is now available free online. You can read the paper with at Elsevier’s Website for the publishing journal (American Journal of Obstetrics and Gynecology – Global Reports), or on the government’s National Institute…

Dr. Marchand’s New Network Meta Analysis of Endometrial Ablation Devices is Now Free Online at BMJ

Dr. Greg Marchand’s latest research article “First and second-generation endometrial ablation devices: A network meta-analysis” has just been published and is now available complete free online on the BMJ website. This network meta-analysis is the largest study to date to look at the wide range of first and second generation endometrial ablation device and to…